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Laboratory profiles: Fundamental to the routine of clinical analysis laboratories
Laboratory profiles are a set of tests used to assess the functioning of the body's organs and systems by analyzing markers present in biological samples. They are fundamental in the routine of clinical analysis laboratories and form a strategic part of diagnostic procedures, as they help to detect metabolic alterations, identify risk factors, monitor treatments and follow the evolution of various clinical conditions.
Ebram offers ready-to-use reagents, compatible with the equipment on the market, with specialized technical support and different presentations, offering security and practicality for laboratories wishing to expand and qualify their range of tests.
Lipid profile
Reagents marketed by Ebram:
- Total Cholesterol (QUIMICOL - COLESTEROL)
- Triglycerides (CHEMITRI - TRIGLYCERIDES)
- HDL Cholesterol (QUIMICOL - H - HDL CHOLESTEROL)
Calculated markers:
- LDL and VLDL
The lipid profile is one of the most requested tests in clinical biochemistry. It assesses blood lipid levels, identifying imbalances related to cardiovascular risk. Alterations in this profile are directly linked to the development of atherosclerosis, myocardial infarction, stroke and other metabolic diseases.
- Total cholesterol: when elevated, is associated with a high risk of angina, heart attacks and strokes.
- Triglycerides: when elevated indicates an increased risk of cardiovascular events.
- LDL and VLDL ("bad cholesterol"): is associated with the formation of plaques in the arteries, indicating a greater risk of atherosclerosis and cardiovascular disease.
- HDL ("good cholesterol"): acts to remove excess cholesterol from the bloodstream.
Monitoring this profile is essential for the prevention and treatment of dyslipidemia, especially in patients with diabetes, obesity or a family history of cardiovascular disease. This is why lipid profile tests are indispensable in routine check-ups.
Liver Profile
Reagents marketed by Ebram:
- ALT/TGP (CHEMIALT - ALT/TGP)
- AST/TGO (CHEMAST - AST/TGO)
- Alkaline phosphatase (QUIMIFAL - ALKALINE PHOSPHATASE)
- GT Range (QUIMIGAMA - GAMA GT)
- Total bilirubin (QUIMIBIL - T - TOTAL BILIRRUBIN)
- Direct bilirubin (QUIMIBIL - D- DIRECT BILIRRUBIN)
- Albumin (QUIMIALB - ALBUMIN)
- Total Protein (QUIMIPROT - PROTEÍNA TOTAL)
- Prothrombin Time (EBCOAG TP - TEMPO DE PROTROMBINA)
The liver profile, or hepatogram, is essential for assessing the function of the liver and bile ducts. The tests are essential for diagnosing and monitoring liver diseases such as hepatitis, hepatic steatosis and cirrhosis, as well as assessing drug toxicity.
- ALT/TGP and AST/TGO: enzymes indicative of liver damage or inflammation, with ALT/TGP being the most liver-specific enzyme.
- Alkaline phosphatase: elevated in biliary obstructions, liver or bone diseases.
- Gama GT: is an indicator of cholestasis and is often altered in cases of excessive alcohol consumption.
- Bilirubin: elevated in liver dysfunction or bile duct obstruction. Its elevation can cause jaundice.
- Albumin: low levels suggest a drop in liver synthesis function or malnutrition.
- Prothrombin time (PT): measures coagulation capacity, a function related to the hepatic synthesis of coagulation factors.
This profile allows for a comprehensive analysis of liver status and is essential for diagnosis and therapeutic monitoring.
Renal Profile
Reagents marketed by Ebram:
- Urea (QUIMIURE - UREIA)
- Creatinine (QUIMICREA - CREATININE)
- Proteinuria (CHEMIPROT - U - PROTEINUria)
- Phosphorus (CHEMIFOS - Phosphorus)
- Uric acid (QUIMIURIC - URICO ACID)
- Chlorides (QUIMICLORO - CLORETOS)
- Calcium (CHEMICAL - CALCIUM)
This profile is aimed at assessing kidney function, which is essential for diagnosing and monitoring dysfunctions in the kidneys, the organ responsible for filtering the blood, regulating electrolytes and eliminating toxic substances through the urine. Changes in this profile can indicate anything from dehydration to more serious conditions, such as acute or chronic kidney failure.
- Urea: produced from the breakdown of proteins, its concentration increases in cases of kidney dysfunction, dehydration or a high-protein diet.
- Creatinine: one of the main indicators of kidney function. Elevations indicate renal impairment.
- Proteinuria: the presence of protein in the urine indicates glomerular damage.
- Phosphorus, calcium and chlorides: changes in these electrolytes help to identify metabolic imbalances common in kidney patients.
This set of tests is also essential in evaluations of patients with hypertension, diabetes, nephrotoxic drugs or pre-surgery.
Cardiac Profile
Reagents marketed by Ebram:
- Total CK (QUIMINAC - CKNAC)
- CK-MB (KIMIMB - CKMB)
- Troponin I (Rapid Test)
- Turb PCR - Ultrasensitive
The cardiac profile is essential for detecting damage to the heart muscle. It is used in medical emergencies and to monitor patients with chest pain, arrhythmias, heart failure and suspected acute myocardial infarction.
- Total CK: is an enzyme found in the heart, brain and skeletal muscle. It can increase in various muscle injuries and is not specific to the heart. This marker should be used in conjunction with CK-MB.
- CK-MB: is one of the most common cardiac markers, being more specific to the heart. It is used to detect heart attacks and to monitor reinfarction.
- Troponin I: a protein that is highly specific to the heart muscle. Its elevation is considered the gold standard for diagnosing heart attacks.
- Ultrasensitive PCR: measures very low levels of C-reactive protein in the blood. Unlike other markers, it is not used for direct diagnosis of heart attacks, but rather as an indicator of cardiovascular risk. High values reflect the presence of low-grade inflammation in the blood vessels, associated with the development and progression of atherosclerosis.
The joint interpretation of these markers allows for a more precise and safer approach to the care of patients with suspected cardiac events.
Pancreatic Profile
Reagents marketed by Ebram:
- Amylase (QUIMIAMIL - AMILASE)
- Lipase (QUIMILIP - LIPASE)
- Glucose (QUIMIGLIC - OX - GLICOSE OXIDASE)
This profile is requested in the investigation of diseases affecting the pancreas, such as acute and chronic pancreatitis, as well as helping to control metabolic diseases such as diabetes mellitus.
- Amylase: digestive enzyme. Its increase is related to acute pancreatitis, pancreatic obstruction and mumps.
- Lipase: a more specific and sensitive enzyme than amylase for the diagnosis of pancreatitis.
- Glucose: essential in monitoring glycemia, especially in controlling type 1 and 2 diabetes.
Monitoring these markers makes it possible to detect early changes in pancreatic function and guide more assertive therapeutic approaches.
Electrolytic profile
Reagents marketed by Ebram:
- Chlorides (QUIMICLORO - CLORETOS)
- Calcium (CHEMICAL - CALCIUM)
- Magnesium (QUIMIMAG - MAGNESIUM)
- Phosphorus (CHEMIFOS - Phosphorus)
This profile assesses the concentration of the main electrolytes in the blood. It is used to assess hydroelectrolyte balance, which is crucial for the proper functioning of various bodily functions, such as nerve impulse transmission, muscle contraction and acid-base balance.
- Chlorides: related to acid-base balance, is altered in digestive and renal losses
- Calcium: participates in coagulation, neuromuscular transmission and bone metabolism.
- Magnesium: enzyme cofactor. Low levels can cause arrhythmias.
- Phosphorus: changes are associated with kidney disease, hormonal and bone disorders.
Electrolyte analysis is essential for fluid management, identification of metabolic disorders and safety in hospital procedures.
Laboratory profiles provide a systemic view of the patient's health and are indispensable in clinical practice. By bringing together several tests in a single request, they optimize time, increase diagnostic assertiveness and make the laboratory routine more organized and efficient
Ebram offers a complete portfolio of reagents for the main laboratory profiles, guaranteeing standardized results, safety and specialized scientific support.
For more information about the products and their applications, contact our team: SAC 0800 500 2424 | e-mail: [email protected]
Commercial department: 11 2291-2811 - e-mail: [email protected]
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